四逆散治疗胃食管反流性咳嗽68例

Treating 68 Cases of Gastroesophageal Reflux Cough by SiNi Powder

目的:观察四逆散治疗胃食管反流性咳嗽(GERC)的临床疗效。方法:将136例患者随机分为观察组、对照组各68例,观察组给予四逆散治疗,对照组给予奥美拉唑胶囊、硫糖铝悬液、吗丁啉片等西医常规治疗。观察2组胃镜检查结果及临床疗效。结果:总有效率观察组为94.1%,对照组为82.3%,2组比较差异有统计学意义(P<0.05)。胃镜分级情况2组治疗后均明显好转(P<0.05),观察组改善更明显(P<0.05)。结论:四逆散加减治疗GERC临床疗效显著,可保护食管黏膜,促进炎症修复。

Objective： To observe clinical effects of SiNi powder in treating gastroesophageal reflux cough（GERC）. Methods： Altogether 136 patients were randomized into the observation group and the control group, 68 cases each group, the observation group were treated with SiNi powder, the control group received routine treatment of western medicine including omeprazole capsules, sucralfate suspension, domperidone tablets and others. To observe clinical effects and gastroscopy between both groups. Results： Total effective rate of the observation group was 94.1%, higher than 82.3% of the control group, the difference had statistical meaning（P〈0.05）. Gastroscopy classification improved obviously in both groups after treating（P〈0.05）, the improvements of the observation group was more notable（P〈0.05）.Conclusion： Modified SiNi powder is effective in treating GERC notably, it could protect esophageal mucosa and promote the repair of the inflammation.