桂枝茯苓丸加减治疗输卵管阻塞性不孕症36例

Modified GuiZhiFuLing Pills in Treating 36 Patients with Fallopian Tube Obstruction Infertility

目的:观察桂枝茯苓丸加减治疗输卵管阻塞性不孕症的临床疗效。方法:将72例患者随机分为观察组、对照组各36例。2组均给予西医常规治疗:经期头孢曲松钠4 g和甲硝唑葡萄糖1 g静脉滴注,1次/d,连用5天。观察组每于经期同时于给予桂枝茯苓丸,水煎分服,每日1剂,连续5天。2组均连续治疗3个月经周期。结果:总有效率观察组为94.44%,对照组为61.11%,差异具有统计学意义(P<0.05)。观察组患者输卵管通畅情况优于对照组(P<0.05)。观察组持续妊娠率高于对照组(P<0.05);流产率2组相当(P>0.05);异位妊娠率观察组低于对照组(P<0.05)。结论:桂枝茯苓丸加减治疗输卵管阻塞性不孕症临床疗效显著,输卵管通畅率高,持续妊娠率高,流产率、异位妊娠率低。

Objective： To survey clinical effects of modified GuiZhiFuLing pills in treating fallopian tube obstruction infertility. Methods： Seventy-two patients were randomly allocated to the observation group and the control group. Both groups received routine treatment of western medicine： intravenous dripping of ceftriaxone sodium, 4g,and metronidazole glucose, 1g, during the menstrual period, once per day, for five consecutive days. The observation group began to take GuiZhiFuLing pills when the patients were in the period, water decocted, one dose per day, for five consecutive days. Both groups were treated for three menstrual cycles. Results： Total effective rate of the observation group was 94.44%, higher than 61.11% of the control group, the difference demonstrated statistical meaning（P〈0.05）. The observation group was superior to the control group in fallopian tube patency conditions（〈P0.05）. The observation group was higher than the control group in the rate of sustained pregnancy（P〈0.05）; both groups are equivalent in abortion rate（P〉0.05）; the observation group was lower than the control group in ectopic gestation rate（P〈0.05）. Conclusion： modified GuiZhiFuLing pills could obtain notable effects in treating fallopian tube obstruction infertility with the advantages of high patency rate of fallopian tube, high sustained pregnancy rate, low abortion rate and ectopic gestation rate.