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慢性丙型肝炎患者个体化治疗方案疗效分析

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摘要 丙型肝炎病毒(HCV)主要经血液传播,呈全球性流行。全世界HCV平均感染率约为3%,我国HCV携带率达3.2%,属高流行区。丙型肝炎起病隐匿,慢性化高,并与肝硬化、肝细胞肝癌高度相关,在欧美及日本等地区高发,目前无疫苗可用于有效预防。因此,早期诊断和及时治疗是控制HCV感染流行的唯一手段。在我国,慢性丙型肝炎(CHC)患者多以HCV基因1型为主,属难治型CHC,且大多患者为中老年患者,对于目前国际公认的标准治疗方案干扰索(IFN)联合利巴韦林治疗丙型肝炎患者,易出现耐受性差,对患者的依从性有一定影响,致使许多患者疗程未结束而被迫终止治疗。
作者 靖军
出处 《山西医药杂志》 CAS 2015年第19期2302-2305,共4页 Shanxi Medical Journal
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