胃肠道间质瘤MSCT双期增强征象与病理危险度的相关性研究

Correlative study of dual-phase contrast enhanced MSCT imaging features and clinicopathological risk grades of gastrointestinal stromal tumors

目的探讨胃肠道间质瘤(GISTs)MSCT双期增强征象与病理危险度的相关性。方法回顾性分析73例经病理和免疫组化证实的GISTs的MSCT双期增强征象与病理危险程度分级的关系。结果不同病理危险度GISTs的位置、形态、生长方式、有无钙化与溃疡、强化程度比较差异均无统计学意义(P>0.05),而肿瘤大小、强化方式、瘤周脂肪间隙、瘤周及瘤内有无血管比较差异均有统计学意义(P<0.05)。MSCT双期增强预评估GISTs良恶性倾向与病理危险度分级呈高度相关性(r=0.7682)。结论 MSCT双期增强像征能反映GISTs的病理危险度,有助于术前预评估GISTs的生物学行为和制定合理的治疗方案。

Objective To investigate the correlation of dual-phase contrast enhanced MSCT imaging fea-tures and clinicopathological risk grades of gastrointestinal stromal tumors （GISTs）. Methods A retrospective analy-sis was performed to analyze the dual-phase contrast enhanced MSCT imaging features and clinicopathological risk grades of 73 patients with pathologically and immunohistochemically confirmed GISTs. Results GISTs showed no statistically significant difference in location, growth pattern, shape, calcification and ulcer, enhanced degree between different clinicopathological risk grade groups （P〉0.05）, but exhibited significant difference in size, enhanced pattern, surrounding fat interspace and appearance vessel-like artery shadow （P〈0.05）. Benign and malignancy tendency as-sessed by dual-phase contrast enhanced MSCT features of GISTs had high correlation with clinicopathological risk grades （r=0.7682）. Conclusion Dual-phase contrast enhanced MSCT imaging characteristics can be used to predict GISTs clinicopathological risk, and can help evaluate biological behavior of GISTs on pre-surgery and institute ratio-nal treatments.