二苄基二硒醚对苯酚羟化反应的催化性能研究

Catalytic Performance Study on Dibenzyldiselenide to Hydroxylation of Phenol

以二苄基二硒醚为催化剂、过氧化氢为氧化剂,研究苯酚的羟化反应,考察了溶剂种类、催化剂用量、反应温度、反应时间等一系列因素对苯酚转化率和苯二酚选择性及收率的影响,并找出最佳反应条件,即m(催化剂)∶m(苯酚)=1∶10,n(过氧化氢)∶n(苯酚)=5∶2,反应温度为80℃,反应时间为2 h,得到苯酚转化率为40.7%,产品选择性为87.0%。

With dibenzyldiselenide serves as catalyst, hydrogen peroxide as oxidizing agent, the hydyoxylation of phenol was studied. The influences of a series of factors as the variety of solvent, catalyst dosage, reaction temperature and reaction time etc. on the phenol conversion and the selectivity and the yield of benzodiazepines were studied. The best reaction conditions are：m（ catalyst）∶m（ phenol） = 1∶10, n（ hydrogen peroxide）∶n（ phenol） = 5∶2, reaction temperature is 80℃, reaction time is 2 h, phenol conversion is 40.7 % and product selectivity is 87.0 %.