胃食管反流病与慢性咽炎关系的临床研究

Clinical analysis of the relationship of gastro-esophageal reflux disease and the cause of chronic pharyngitis

目的探讨胃食管反流病与慢性咽炎发病的临床关系。方法纳入慢性咽炎门诊患者40例，随机分为研究组和对照组。研究组采用半夏厚朴汤、莫沙必利联合兰索拉唑治疗，对照组采用半夏厚朴汤治疗，并对患者治疗前后进行问卷评分，比较两组治疗前后的情况。结果研究组治疗后，临床症状显著减轻，差异具统计学意义（P〈0.05）。对照组治疗后，临床症状有一定减轻，差异有统计学意义（P（0.05）。两组治疗前后咽部炎症的有效率分别为85％和55％，差异有统计学意义（P〈0.05）。结论胃食管反流病是慢性咽炎的病因之一，慢性咽炎患者通过抗反流治疗，临床效果显著。

Objective To explore the clinical relationship of gastro-esophageal reflux disease and the cause of chronic pharyngitis. Methods 40 patients with chronic pharyngitis were selected, and randomly divided into the observation group and the control group. The observation group were treated with Pinellia magnolia bark soup and mosapride and lansoprazole, while the control group were treated with Pineilia magnolia bark soup. All the patients were given the questionnaire score before and after the treatment, and compared the situation of the two groups of patients. Results After treatment,the clinical symptoms of the observation group were significantly improved, and the difference was statistically significant （P〈 0. 05）. After treatment, the clinical symptoms of the control group also was reduced, and the difference was statistically significant（P〈0.05）. The effective rate of the two groups before and after treatment were 85 and 55 %, and the difference was statistically significant （P〈 0.05）. Conclusion Gastro-esophageal reflux disease is an important cause of chronic pharyngitis. The clinical effect that patients with chronic pharyngitis treated by anti reflux is remarkable.