摘要
为了持续抑制HBV复制,慢性乙型肝炎(CHB)患者需要长期甚至终生抗病毒治疗,而依从性是影响治疗效果的关键因素之一。回顾了目前CHB患者抗病毒治疗依从性相关研究,包括依从性水平、依从性对治疗效果的影响,总结了影响治疗依从性的因素,分析了目前CHB依从性研究中存在的问题,指出今后研究中应该更加关注如何提高依从性从而改善预后。
In order to achieve the sustained suppression of hepatitis B virus replication,the long- term and even life- long antiviral therapy is needed for patients with chronic hepatitis B（ CHB）. So the adherence to antiviral therapy is one of the critical factors for achieving effective therapy. In this article,the current studies on the adherence to antiviral therapy in patients with CHB are reviewed. The rate of patients＇ adherence to antiviral therapy and its impact on treatment outcome are analyzed,and the influencing factors for adherence are summarized.The existing problems in current studies on adherence are also analyzed. It is proposed that the attention should be focused on how to improve medication adherence so as to improve the prognosis in the future.
出处
《临床肝胆病杂志》
CAS
2015年第10期1735-1739,共5页
Journal of Clinical Hepatology
基金
国家125科技重大专项"艾滋病和病毒性肝炎等重大传染病防治"(2012ZX10002004-006
2012ZX10004904-003-001
2013ZX10002002-006)
北京市医院管理局临床医学发展专项经费资助(XM201308)
国家临床重点专科建设项目(WJWYA-2014-002)
科研基地建设-重大传染病防治协同创新中心(2011协同创新中心
市级
115215)
北京卫生系统高技术人才培养项目基金(2013-3-071
2011-3-083)
关键词
肝炎
乙型
慢性
抗病毒药
病人依从
综述
hepatitis B
chronic
antiviral agents
patient compliance
review
