盐酸利托君与硫酸镁防治先兆早产的临床比较

Clinical Effects Comparison of Ritodrine Hydrochloric or Magnesium Sulfate on the Prevention of Threatened Premature Labor

目的:探讨比较盐酸利托君与硫酸镁防治先兆早产的临床疗效。方法:选取笔者所在医院妇产科2013年1月-2014年12月收治的90例先兆早产患者,将其按照数字表法随机分为研究组和对照组,每组45例。研究组给予盐酸利托君,对照组给予硫酸镁。对比两组患者的起效时间、孕龄延长时间、治疗成功率、不良反应发生率、新生儿存活率、出生体重及Apgar评分的差异。结果:研究组起效时间显著短于对照组(P<0.01),孕龄延长时间明显长于对照组(P<0.01),治疗成功率显著优于对照组(P<0.05);研究组不良反应发生率显著低于对照组(P<0.05);新生儿存活率、出生体重及Apgar评分均优于对照组(P<0.05)。结论:盐酸利托君治疗先兆早产的临床疗效明显优于硫酸镁,临床上值得推广应用。

Objective：To compare the clinical effects of ritodrine hydrochloric or magnesium sulfate on the prevention of threatened premature labor.Method：90 cases of patients with threatened premature labor were treated from January 2013 to December 2014 in obstetrics and gynecology of our hospital and randomly divided into the study group and the control group,45 cases in each group.Patients in the study group were treated by Ritodrine Hydrochloric and patients in the control group were treated by Magnesium Sulfate.The onset time,gestational age longer time,the success rate,incidence of adverse reactions,neonatal survival,birth weight and Apgar score were compared between two groups.Result：The onset time in the study group was significantly less than that in the control group（P〈0.01）.The gestational age longer time in the study group was significantly longer than that in the control group（P〈0.01）.The clinical success rate in the study group was significantly higher than that in the control group（P〈0.05）.The adverse reaction rate in the study group was significantly less than that in the control group（P〈0.05）.The neonatal survival,birth weight and Apgar score in the study group were significantly better than those in the control group（P〈0.05）.Conclusion：Ritodrine Hydrochloric has a better clinical effects on prevention of threatened premature labor,makes it worth for wildly used.