摘要
目的:对男性不育患者进行染色体核型的检测,探讨男性不育与染色体核型异常的关系。方法:按常规方法制作染色体标本的方法,对122例男性不育患者进行核型分析。结果:共检出染色体异常17例,异常率为13.93%。其中性染色体异常12例,占男性不育患者的9.84%,常染色体异常5例,占男性不育患者的4.10%。在所有的核型中,Klinefelter综合征的发生率最高,占异常核型的23.53%。结论:染色体异常是导致男性不育的重要原因之一,染色体核型分析对男性不育患者的诊断和治疗具有重要的指导意义。
Objectives: To analyze the karyotypes of infertile male patients so as to investigate the relationship between male infertility and chromosome abnormalities. Methods: The chromosome karyotypes of 122 male infertile patients were analyzed by routinely cultured peripheral blood lymphocytes. Results: There were 17 cases of abnormal karyotypes which accounted for 13. 93%,including 12( 9. 84%) cases of sex abnormal karyotype and 5( 4. 10%) cases of autosome abnormal karyotype. The klinefelter syndrome was the most common disease caused by abnormal karyotype and the ratio was 23. 53% in all the abnormal karyotypes. Conclusion: Chromosome abnormality is an important cause of male infertility. Karyotype analysis is important for the diagnosis and treatment of male infertility.
出处
《中国性科学》
2015年第10期82-85,共4页
Chinese Journal of Human Sexuality
基金
河南省科技厅年度计划项目(132300410471)
关键词
男性不育
染色体异常
核型分析
Male infertility
Chromosomal abnormality
Karyrotype analysis