无高血压2型糖尿病患者左心室肥厚的危险因素筛查被引量：4

Risk factors for left ventricular hypertrophy in non-hypertensive patients with type 2 diabetes

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摘要目的了解无高血压的2型糖尿病患者发生左心室肥厚（LVH）的原因。方法检测197例无高血压2型糖尿病患者空腹血糖、胰岛素、糖化血红蛋白（HbA1c）、尿白蛋白／肌酐（A1b／Cr）、血脂、电解质等水平，并进行心脏超声检查。结果据心脏超声将患者分为有LVH组和无LVH组。LVH组的A1b／Cr、血钠指标及肥胖、微量白蛋白尿发生率均明显高于无LVH组；多重线性回归显示左心室质量指数与A1b／Cr呈正相关；Logistic回归显示LVH与微量白蛋白尿及肥胖的发生显著相关。结论微量白蛋白尿与肥胖是无高血压2型糖尿病患者发生LVH的危险因素。 Objective To screen risk factors other than hypertension for left ventricular hypertro- phy（LVH） in patients with type 2 diabetes mellitus（T2DM）. Methods In this echocardiographic study, 197 non-hypertensive mellitus （T2DM） patients were enrolled. Fasting blood glucose,insulin, HbAlc, uri- nary albumivr/creatinine（Alb/Cr） , blood lipids and serum electrolytes were measured. Results Com- pared with non-LVH group,the incidence of microalbuminuria as well as obesity,Alb/Cr and serum sodi- um in LVH group were significantly higher. Multiple linear regression analysis showed that left ventricular mass index was positively associated with Alb/Cr. Logistic regression analysis showed that microalbumin- uria and obesity were independent risk factors for LVH. Conclusion Microalbuminuria and obesity are independent risk factors for LVH in T2DM patients without hypertension.

作者宋慧琴文重远程俊何文芳

机构地区武汉大学人民医院内分泌科广东省英德市人民医院

出处《临床内科杂志》 CAS 2015年第10期672-674,共3页 Journal of Clinical Internal Medicine

关键词 2型糖尿病左心室肥厚微量白蛋白尿肥胖 Type 2 diabetes Left ventrieular hypertrophy Mieroalbuminuria Obesity

分类号 R587.1 [医药卫生—内分泌]

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