新疆产白花曼陀罗种子化学成分研究

Study on Chemical Constituents in Seeds of Datura metel from Xinjiang

目的：对新疆产白花曼陀罗种子进行化学成分研究。方法：采用硅胶、ODS以及Sephadex LH-20等色谱技术分离纯化化合物,根据理化性质及波谱数据解析鉴定化合物结构。结果：从白花曼陀罗种子中分离并鉴定出10个化合物,分别为：异嗪皮啶（1）、滨蒿内酯（2）、曼陀罗萜二醇（3）、对苯二酚（4）、Arenarine D（5）、香草醛（6）、N-阿魏酰酪胺（7）、东莨菪内酯（8）、β-谷甾醇（9）、Hyoscyamilactol（10）。结论：其中,化合物1、2为首次从茄科植物中分离得到,化合物3～8为首次从该植物中分离得到。

Objective：To study the chemical constituents in the seeds of Datura metel from Xinjiang Province. Methods：The con- stituents were isolated and purified by silica gel, ODS and Sephadex LH-20 column chromatographic methods. Their chemical structures were analyzed and identified on the basis of physical and chemical properties and spectral data. Results ： Ten compounds were isolated and identified as Isofraxidin （ 1 ）, Scopatone （ 2 ）, Daturadiol （ 3 ）, 1,4-Benzenediol （4）, Arenarine D （ 5 ）, Vanillin （ 6 ）, N-trans-Feruloyl- tyramine （7）, Scopoletin （ 8 ）,/3-Sitosterol （ 9 ） and Hyoscyamilactol （ 10 ）. Conclusion ： Compounds 1 and 2 are firstly isolated from the plants in Solanaceae, compounds 3 -8 are firstly isolated from this plant.