宫颈癌患者放疗后生活质量现状调查及影响因素分析

Quality of life and its affecting factors of post-radiotherapy cervical cancer patients

目的：调查宫颈癌患者放射治疗后的生活质量现状，探讨其影响因素，为改善其生活质量提供依据。方法采用宫颈癌生存质量评估量表（ FACT-Cx）对792例放疗后1年内的宫颈癌患者进行调查，对调查结果采用 DPS 数据系统软件进行分析。结果792例患者生存质量总分为（119.55±18．21）分，其中生理状况（22.08±4.56）分，社会/家庭状况（18.29±4.47）分，情感状况（17.89±4.74）分，功能状况（16.78±4.68）分，宫颈癌特异模块（44.51±5.05）分。单因素分析显示，不同医疗费用支付方式、家庭月收入、放疗结束后时间、婚姻状况及有无宗教信仰、放射性直肠炎、放射性膀胱炎、下肢水肿、更年期样症状、性生活宫颈癌患者放疗后FACT-Cx评分比较，差异均有统计学意义（P＆lt;0.05）。多元线性回归分析显示，放射性直肠炎、放疗后时间、医疗费用支付方式为宫颈癌患者放射治疗后生活质量的主要影响因素，其次为家庭月收入、性生活、临床分期、下肢水肿、宗教信仰。结论宫颈癌患者放疗后1年内的生活质量水平处于中等偏上，生活质量受多种因素影响，应加强对放疗相关并发症、恢复期性生活的干预，以提高患者生活质量。

Objective To evaluate the quality of life （ QOL） status of post-radiotherapy cervical cancer patients, to investigate the possible factors what affect the QOL and to provide consults for improving the patients QOL. Methods Within one year after radiotherapy, 792 cervical cancer patients were surveyed and analyzed by the quality of life evaluation scale of cervical cancer （ FACT-Cx） and self-design questionnaires. The results of survey were analyzed by DPS data system software. Results The total grade points of QOL of the patients were （119. 55 ± 18. 21）, in which the physiological status point was （22. 08 ± 4. 56）, social/family status point （18. 29 ± 4. 47）, emotion status point （17. 89 ± 4. 74）, function status point was （16. 78 ± 4. 68） and the point of peculiar module of cervical cancer （44. 51 ± 5. 05）. Single factor analysis revealed that patients with different payment methods of medical cost, family income, time of post-radiotherapy, marriage status, having religion or not, factitial proctitis, radiocystitis, edema of lower extremity, menopausal symptoms and sexual life had different degree of QOL with statistical significance （P〈0. 05）. The multiple liner regression analysis displayed factitial proctitis, time of post-radiotherapy and payment methods of medical cost were mail influencing factors on QOL of cervical cancer patients, followed by monthly family income, sexual life, clinical stages, edema of lower extremity, religious faith. Conclusions Generally, QOL of cervical cancer patients are better than average within one year after radiation therapy and it is affected by multiple factors. In order to improve the QOL of post-radiotherapy in cervical cancer patients, it must be enhanced the intervention of complication related to the radiotherapy and sexual life of convalescence.