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CART技术治疗血液恶性肿瘤研究进展 被引量:10

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摘要 CART细胞是指嵌合抗原受体(CAR)的T细胞,通过基因转导使T淋巴细胞表达特定的CAR,构建特异性CART细胞,从而特异性识别靶抗原,杀伤靶细胞[1]。CART细胞在体外及体内均具有对特定肿瘤抗原的高度亲和性和对表达抗原的肿瘤细胞的高效杀伤特性[2]。CART细胞技术可以特异性杀死肿瘤细胞,不会引起移植物抗宿主反应,不良反应小,患者耐受性好。
出处 《现代医药卫生》 2015年第21期3256-3259,共4页 Journal of Modern Medicine & Health
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  • 2朱昕赟,姚军霞.CART技术及其临床应用[J].临床血液学杂志,2015,28(3):428-431. 被引量:8
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