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2例急性肺栓塞致心脏骤停成功救治的临床分析并文献复习 被引量:3

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摘要 肺血栓栓塞症( pulmonary thromboembolism , PTE)是内源性和外源性栓子堵塞肺动脉引起肺循环障碍的临床和病理生理综合征,其发生率、病死率和误诊率都较高。住院患者虽经过有效的预防性治疗,但病死率仍达到15%[1]。这部分死亡患者中多数为急性高危PTE,如果有机会确诊,进行紧急溶栓可以显著提高生存率。但是其中约41%的急性高危PTE通过各种机制可导致心脏骤停,此类患者很难有机会进一步检查确诊并进行有效的针对性治疗,尤其在急诊科,多数已进入心肺复苏( CPR)流程而无法获取详细的临床资料,因而其病死率高达65%~95%[2]。最新的ACLS指南没有就此类患者的常规性或经验性溶栓做出明确的推荐意见。现将我院ICU近期成功救治的2例急性PTE致心脏骤停( CA)做一分析,以期提供参考。
出处 《中国急救医学》 CAS CSCD 北大核心 2015年第10期925-928,共4页 Chinese Journal of Critical Care Medicine
基金 浙江省教育厅科研基金支持项目(Y201226217) 浙江省人口和计划生育科技基金支持项目(JSW-2012-a007)
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  • 1Wood KE. Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmo- nary embolism[J]. Chest, 2002, 121(3) : 877 -905.
  • 2Bailn MR, Cuadra JA, Hoyos EA. Thrombolysis during cardiop- ulmonary resuscitation in fulminant pulmonary embolism: a review [J]. Grit Care Med, 2001,29(I) : 2211 -2219.
  • 3Prosen G, Krinari6 M, Zavrnik J, et al. Impact of modified treatment in echocardiographicaUy confirmed pseudo - pulseless e- lectrical activity in out - of - hospital cardiac arrest patients with constant end- tidal carbon dioxide pressure during compression pauses[J]. J Int Med Res, 2010, 38(4) : 1458 -1467.
  • 4British Thoracic Society guidelines for the management of suspec- ted acute pulmonary embolism[J]. Thorax, 2003, 58(6) : 470 - 483.
  • 5Jimnez D, Aujesky D, Dfaz G, et al. Prognostic significance of deep vein thrombosis in patients presenting with acute symptomatic pulmonary embulism[J]. Am J Respir Crit Care Med, 2010, 181 (9) : 983 -991.
  • 6Fischer Jl, Huis in't Veld MA, Orland M, et al. Diagnosis of near - fatal pulmonary embolus - in - transit with focused eehoear- diography[ J]. J Emerg Med, 2013, 45(2) : 232 -235.
  • 7Perkins ZB, Mitchell C, Donald O. Prehospital thrombolysis of amassive pulmonary embolus [ J ]. Emerg Med J, 2008, 25 ( 5 ) : 303 - 304.
  • 8Larsen JM, Ravkilde J. Acute coronary angiography in patients re- suscitated from out - of - hospital cardiac arrest - a systematic re- view and meta- analysis [ J ]. Resuscitation, 2012, 83 ( 12 ) : 1427 - 1433.
  • 9Tapson VF. Thrombolytic therapy in acute pulmonary embolism [J]. Curr opin cardiol, 2012, 27(6) : 585 -591.
  • 10Pullarkat V, Ngo M, Iqbal S, et al. Detection of lupus anticoagulant identifies patients with autoimmune haemolytic anaemia at in- creased risk for venous thromboembolism [ J ]. Br J Haematol, 2002, 118(4): 1166-1169.

二级参考文献37

  • 1李瑜霞,李永秋,卢宝全,刘素之.脑出血合并肺栓塞抗凝治疗1例报告[J].中风与神经疾病杂志,2006,23(6):744-744. 被引量:1
  • 2Janata K,Holzer M,Laggner AN,et al.Cardiac troponin T in the severity assessment of patients with pulmonary embolism:cohort study.BMJ,2003,326:312-313.
  • 3Horlander KT,Leeper KV.Troponin levels as a guide to treatment of pulmonary embolism.Curr Opin Pulm Med,2003,9:374-377.
  • 4Manier G,Castaing Y,Guenard H.Determinants of hypoxemia during the acute phase of pulmonary embolism in humans.Am Rev Respir Dis,1985,132:332-338.
  • 5Tanus-Santos JE,Gordo WM,Udelsmann A,et al.Nonselective endothelin-receptor antagonism attenuates hemodynamic changes after massive pulmonary air embolism in dogs.Chest,2000,118:175-179.
  • 6Grifoni S,Olivotto I,Cecchini P,et al.Short-term clinical outcome of patients with acute pulmonary embolism,normal blood pressure,and echocardiographic right ventricular dysfunction.Circulation,2000,101:2817-2822.
  • 7Baillard C,Boussarsar M,Fosse JP,et al.Cardiac troponin Ⅰ in patients with severe exacerbation of chronic obstructive pulmonary disease.Intensive Care Med,2003,29:584-589.
  • 8Coma-Canella I,Gamallo C,Martinez Onsurbe P,et al.Acute right ventricular infarction secondary to massive pulmonary embolism.Eur Heart J,1988,9:534-540.
  • 9Dschietzig T,Laule M,Alexiou K,et al.Coronary constriction and consequent cardiodepression in pulmonary embolism are mediated by pulmonary big endothelin and enhanced in early endothelial dysfunction.Crit Care Med,1998,26:510-517.
  • 10Feng J,Schaus BJ,Fallavollita JA,et al.Preload induces troponin Ⅰ degradation independently of myocardial ischemia.Circulation,2001,103:2035-2037.

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