丙泊酚静脉全麻与七氟醚吸入麻醉在腹腔镜胆囊切除术中的临床效果比较

Comparison of Anesthetic Effect of Propofol Intravenous Anesthesia and Sevoflurane Inhalation Anesthesia for Laparoscopic Cholecystectomy

目的探讨丙泊酚静脉全麻与七氟醚吸入麻醉在腹腔镜胆囊切除术中的临床麻醉效果。方法选取2011年10月～2014年12月进行腹腔镜胆囊切除术治疗的124例患者,分为对照组62例和观察组62例,对照组患者采用丙泊酚静脉全麻,观察组患者采用七氟醚吸入麻醉,对比观察两组麻醉方法得临床应用效果。结果1血流动力学比较：两组患者的T1、T2、T3和T4时刻的HR与MRP比较无显著差异（P〉0.05）,HR与MRP均在T2和T3时刻上升,并于T4时刻再降低。2术后恢复情况比较：观察组患者的术后自主呼吸时间、苏醒时间、拔管时间及指令性反应时间均显著短于对照组患者,P〈0.05,差异具有统计学意义。结论丙泊酚静脉全麻与七氟醚吸入麻醉在腹腔镜胆囊切除术中均能较好的维持围手术期的血流动力学稳定,但七氟醚吸入麻醉患者的术后恢复时间更短,更适合此类手术。

Objective To investigate clinical anesthesia effect of propofol intravenous anesthesia and sevoflurane inhalation anesthesia for laparoscopic cholecystectomy. Methods From 2011 October to 2014 December,124 cases of laparoscopic cholecystectomy were selected in the Second Affiliated Hospital of Shenyang Medical College,they were randomly divided into the control group（ 62 cases）,and the observation group（ 62 cases）; The control group were treated with propofol intravenous anesthesia,and the observation group received by sevoflurane inhalation anesthesia,clinical anesthesia effect was compared between two groups. Results 1comparison of hemodynamics： There was no significant difference in HR and MRP at T1,T2,T3 and T4time between two groups（ P〈0. 05）,HR and MRP were both increased at T2 and T3,and then decreased at the moment of T4. 2The postoperative recovery： in the postoperative spontaneous breathing time,awakening time,extubation time and mandatory reaction time,the observation group was significantly shorter than the control group,P〈0. 05,the difference was statistically significant. Conclusions Propofol intravenous anesthesia and sevoflurane inhalation anesthesia for laparoscopic cholecystectomy can both better maintain the stability of hemodynamics during operation period,but the sevoflurane inhalation anesthesia has shorter postoperative recovery time,and it is more suitable for the laparoscopic cholecystectomy.