藿香正气水致皮肌炎1例并文献复习

One case of dermatomyositis due to Huoxiangzhengqishui and literature review

1例63岁男性患者,既往体健,因自行服用藿香正气水12支/天致乏力加重、行走困难、腹泻入院,继而出现茶色尿及面颊部皮疹,测血清肌酸激酶(CK)、乳酸脱氢酶(LDH)、天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)增高,经皮肤科、风湿科会诊后诊断为"皮肌炎"。入院后给予注射用甲基强的松龙(80 mg,ivgtt,qd)、注射用氢化可的松(100 mg,ivgtt,tid)抗炎,注射用比阿培南(0.3 g,ivgtt,tid)抗感染,去甲肾上腺素注射液持续微泵维持升压,另辅以护肝、补液及对症支持治疗。入院第6天,复查患者生化指标已基本恢复正常,体温正常,炎症指标下降,面部皮疹结痂,病情好转。

One 63-year-old male patient was hospitalized due to aggravating weakness, walking difficulty and diarrhea followed by dark brown urine and cheek rash after taking Huoxiangzhengqishui 12 pieces per day with the increase of CK, LDH, AST and ALT in patient, the diagnosis was dermatomyositis. After hospitalization, anti-inflammatory therapy with methylprednisolone（80 mg, ivgtt, qd） and hydrocortisone（100 mg, ivgtt, tid）, anti-infection with biapenem（0.3 g, ivgtt, tid）, noradrenaline and other symptomatic supporting therapy including liver protection and fluid infusion were given to him. After 6 days, the patient improved.