中西医结合治疗慢性萎缩性胃炎的效果评价

Effectiveness Evaluation of Combination of Traditional Chineseand Western Medicine Treatment of Chronic Atrophic Gastritis

目的:探讨中西医结合治疗慢性萎缩性胃炎的临床疗效。方法:84例慢性萎缩性胃炎患者按照随机对照法随机分为对照组和观察组各42例。对照组采用常规西药治疗,观察组在对照组基础上口服三九胃泰冲剂和针刺中脘、内关、足三里、气海等穴位,两组均连续治疗12周后评价其临床疗效。结果:治疗4周、8周、12周后,观察组总有效率显著高于对照组(100.00%vs52.38%,88.10%vs69.05%,95.24%vs78.57%,P<0.05);与治疗前比较,两组患者胃痛、胃胀、嗳气、纳差及大便不畅等临床症状评分均显著下降(P<0.05),且观察组下降更为明显(P<0.05);两组不良反应比较,差异无统计学意义(9.53%vs11.90%,P>0.05)。结论:三九胃泰冲剂和针刺穴位可显著改善患者临床症状,提高临床疗效,较单纯使用西药临床效果好。

Objective： To explore the combination of traditional Chinese and Western medicine treatment of chronic atrophic gastritis. Methods： 84 cases of chronic atrophic gastritis were divided into control group（ n = 42） and observation group（ n = 42）. Conventional medical therapy was given to both groups and the observation group received additional Sanjiu Weitai Granules and acupuncture at Zusanli（ ST36）,Neiguan（ PC6）,Zhongwan（ RN12）,Qihai（ RN6）. After 12 weeks,the effects of two groups were compared. Results： After 4,8,12 weeks,the clinical efficacy rate of observation group was higher than the control group＇s（ 100. 00% vs52. 38%,88. 10% vs69. 05%,95. 24% vs78. 57%,P〈 0. 05）. Clinical symptom scores of stomach pain,bloating,poor appetite and bowel movements after therapy were obviously lowerin both groups（ P〈 0. 05）. The observation groupwas better than the control group（ P 〈0. 05）. There was no significant difference in the prevalence of adverse effects between two groups（ 9. 53% vs11. 90%,P〉 0. 05）. Conclusion： Sanjiu Weitai Granules and acupuncture can improve the clinical symptom and effect. The effect is impressively higher than that of Western medicine only.