盐酸多奈哌齐在老年痴呆治疗中的应用研究

Application research of donepezil hydrochloride in the treatment of Alzheimer's disease

目的探究老年痴呆患者采用盐酸多奈哌齐治疗的方法和效果。方法 67例老年痴呆患者,随机分为实验组43例和对照组24例,实验组患者给予盐酸多奈哌齐治疗,对照组患者给予常规治疗,观察患者的治疗效果。结果实验组治疗总有效率为93.0%,对照组治疗总有效率为75.0%,差异有统计学意义(P<0.05)。结论老年痴呆患者采用盐酸多奈哌齐治疗,可促使患者认知能力和日常生活能力的提高,效果显著,不良反应少,可广泛推荐。

Objective To investigate treatment method and effect by donepezil hydrochloride in the treatment of Alzheimer＇s disease.Methods A total of 67 patients with Alzheimer＇s disease were randomly divided into experimental group with 43 cases and control group with 24 cases. The experimental group received donepezil hydrochloride for treatment, and the control group received conventional treatment. Their curative effects were observed.Results The experimental group had total effective rate as 93.0%, and the control group had it as 75.0%. Their difference had statistical significance （P＜0.05）.Conclusion Application of donepezil hydrochloride in the treatment of Alzheimer＇s disease patients can accelerate improvements of cognitive ability and ability of daily life in patients. This method provides remarkable effect, along with few adverse reactions. It is worthy wide promotion.