舒肝宁治疗药物性肝炎的临床疗效分析

Analysis of clinical effect by Shuganning in the treatment of drug-induced hepatitis

目的研究舒肝宁治疗药物性肝炎的临床疗效。方法 60例药物性肝炎患者,随机分为试验组与对照组,各30例。对照组使用硫普罗宁治疗,试验组在对照组的基础上使用舒肝宁治疗,比较两组患者肝功能改善情况。结果治疗前,两组患者丙氨酸转氨酶(ALT)、门冬氨酸转氨酶(AST)、总胆红素(TBIL)比较,差异无统计学意义(P>0.05);治疗后,试验组ALT、AST、TBIL值均优于对照组,差异有统计学意义(P<0.05)。结论使用舒肝宁治疗药物性肝炎,可明显改善患者肝功能,提高临床疗效,值得在临床推广。

ObjectiveTo research clinical effect by Shuganning in the treatment of drug-induced hepatitis.MethodsA total of 60 patients with drug-induced hepatitis were randomly divided into experimental group and control group, with 30 cases in each group. The control group received tiopronin for treatment, and the experimental group received additional Shuganning. Improvements of liver function were compared between the two groups.ResultsThere was no statistically significant difference of alanine aminotransferase （ALT）, aspartate aminotransferase （AST）, and total bilirubin （TBIL） between the two groups before treatment （P＞0.05）. After treatment, the experimental group had better ALT, AST, and TBIL than the control group, and their difference had statistical significance （P＜0.05）.ConclusionImplement of Shuganning in the treatment of drug-induced hepatitis can remarkably improve liver function and clinical effect for patients. It is worth clinical promotion.