去氧孕烯炔雌醇治疗青春期功能性子宫出血的临床疗效

The clinical effects of gestodene- ethinylestradiol in the treatment of adolescent dysfunctional uterine bleeding

目的探讨去氧孕烯炔雌醇治疗青春期功能性子宫出血(青春期功血)的临床疗效。方法选择2014年1月—2015年1月无锡市第二人民医院收治的50例青春期功血患者,采用随机数字表法将患者分为观察组(25例)和对照组(25例)。对照组给予黄体酮胶囊治疗,观察组给予去氧孕烯炔雌醇治疗,比较两组临床疗效、控制止血时间、完全止血时间和出血量、不良反应发生情况。结果观察组总有效率为100.00%,高于对照组的72.00%,差异有统计学意义(P<0.05)。观察组控制止血时间、完全止血时间短于对照组,出血量少于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论去氧孕烯炔雌醇治疗青春期功血具有较好的临床疗效,可显著缩短控制止血时间、完全止血时间,减少出血量,不良反应少。

Objective To study the clinical effects of gestodene - ethinylestradiol in the treatment of adolescent dys-functional uterine bleeding. Methods A total of 50 adolescent dysfunctional uterine bleeding patients were selected from Janu-ary 2014 to January 2015 in the Second People＇s Hospital of Wuxi City,they were randomly divided into the observation group （25 cases）and the control group（25 cases）. The control group was treated with progesterone capsule,the observation group was treated with gestodene - ethinylestradiol. The clinical effects,control bleeding time,complete hemostasis time and amount of bleeding,incidence of adverse reactions between the two groups were compared. Results The total effective rate of the obser-vation group was 100. 00% ,which was higher than 80. 00% of the control group（P ﹤ 0. 05）. The control bleeding time,com-plete hemostasis time of the observation group were shorter than those of the control group,amount of bleeding were less than those of the control group（P ﹤ 0. 05）. There was no statistically significant difference in the adverse reactions rate between the two groups（P ﹥ 0. 05）. Conclusion Gestodene - ethinylestradiol has good clinical efficacy in the treatment of adolescent dys-functional uterine bleeding,can significantly shorten the control bleeding time,complete hemostasis time,decrease the amount of bleeding,and has less adverse reactions.