磺胺嘧啶银治疗烧伤感染创面的临床疗效

Effect of silver sulfadiazine in treating infection of burn

目的探讨磺胺嘧啶银治疗烧伤感染创面的临床疗效。方法选取2014年2月—2015年2月吉安市中心人民医院收治的烧伤感染创面患者80例,采用随机数字表法将患者分为观察组与对照组,各40例。观察组患者予以磺胺嘧啶银治疗,对照组患者予以庆大霉素治疗。观察两组患者临床疗效、疼痛程度、换药次数、创口愈合时间及不良反应发生情况。结果观察组总有效率高于对照组,差异有统计学意义(P<0.05);观察组患者疼痛程度优于对照组,差异有统计学意义(P<0.05);观察组患者换药次数少于对照组,创口愈合时间短于对照组,差异有统计学意义(P<0.05);两组患者均未发生严重不良反应。结论磺胺嘧啶银治疗烧伤感染创面的临床疗效显著,可缓解患者疼痛、减少换药次数、缩短创口愈合时间,且不良反应少。

Objective To explore the effect of silver sulfadiazine in treating infection of burn. Methods A total of 80 patients with infection of burn were selected in the Central People＆#39;s Hospital of Ji＆#39;an from February 2014 to February 2015, according to random number table,they were divided into observation group and control group,40 cases in each group. Obser-vation group were given silver sulfadiazine treatment,control group were given gentamicin treatment. Clinical effect,pain de-gree,frequency of dressing change,wound healing time and incidence of adverse reactions between the two groups were com-pared. Results The total effective rate of observation group was higher than that of control group（P ﹤ 0. 05）;pain degree of observation group was better than that of control group（P ﹤ 0. 05）;frequency of dressing change of observation group was less than that of control group,wound healing time of observation group was shorter than that of control group（P ﹤ 0. 05）;no one of the two groups occurred serious adverse reactions. Conclusion Silver sulfadiazine has notable curative effect in the treatment of infection of burn,can alleviate patients＆#39; pain,reduce the switching frequency,shorten the wound healing time and has less ad-verse reactions.