大柴胡汤治疗急性胰腺炎40例

Forty Cases of Acute Pancreatitis Treated with Major Bupleurum Decoction

目的:观察大柴胡汤治疗急性胰腺炎的临床疗效及对患者血清IL-6和TNF-α的影响。方法:80例急性胰腺炎患者按照随机数字表法随机分为对照组与治疗组,每组40例。两组患者均给予西医对症治疗,治疗组在对照组的基础上加用大柴胡汤治疗。结果:治疗组有效率为90.0%,对照组有效率77.5%,治疗组优于对照组(P<0.05);治疗组治疗后血清IL-6及TNF-α水平优于对照组(P<0.05)。结论:大柴胡汤治疗急性胰腺炎疗效显著,且能显著降低患者血清IL-6及TNF-α水平。

Objective： To observe the clinical curative effect of Major Bupleurum Decoction on acute pancreatitis and its influence on the patients＇ serum IL-6 and TNF-α. Methods： Eighty patients with acute pancreatitis were divided into the control group and the treatment group according to random number table method,with 40 cases in each group. All the patients were first given symptomatic Western medicine,then the ones in the treatment group were added Major Bupleurum Decoction. Results： The effective rate of the treatment group was 90. 0%,while that of the control group was 77. 5%; And the treatment group was better than the control group（ P〈0. 05）. After the treatment,serum IL-6 and TNF-α level of the treatment group were better than those of the control group（ P〈0. 05）. Conclusion： Major Bupleurum Decoction has remarkable clinical curative effect on acute pancreatitis,and can greatly reduce the patients＇ serum IL-6 and TNF-α level.