清肝和胃方治疗肝胃郁热型反流性食管炎临床研究

The Clinical Research into Reflux Esophagitis of Stagnated Heat of Liver and Stomach Type Treated with Decoction for Clearing Liver and Harmonizing Stomach

目的:观察清肝和胃方治疗肝胃郁热型反流性食管炎的临床疗效。方法:将88例患者随机分为观察组和对照组,每组各44例。观察组以清肝和胃方口服,对照组雷贝拉唑片10 mg,每天2次,莫沙比利10 mg,每天3次,饭前0.5 h服用。两组均以8周为1个疗程。结果:观察组有效率为93.2%,对照组有效率为75.0%,两组有效率比较,差异具有统计学意义(P<0.05);治疗后观察组胃镜观察指标积分水平显著低于对照组,两组间比较差异有统计学意义(P<0.05)。结论:清肝和胃方治疗肝胃郁热型反流性食管炎疗效满意。

Objective： To observe the clinical curative effect of Decoction for Clearing Liver and Harmonizing Stomach（ DCLHS） on reflux esophagitis of stagnated heat of liver and stomach type. Methods： Eighty-eight patients were randomly divided into the observation group and the control group,with 44 cases in each group. The ones in the observation group were treated with DCLHS,while the ones in the control group were given rabeprazole tablets 10 mg each time,2 times a day,and mosapride 10 mg each time,3times a day half an hour before meals. The two groups both regarded 8 weeks as one course. Results： The effective rate of the observation group was 93. 2%,while that of the control group was 75. 0%; And the difference between the two groups were statistically significant（ P〈0. 05）. After the treatment,the endoscopic observation index score of the observation group was significantly lower than that of the control group,And the difference between the two groups were statistically significant（ P〈0. 05）. Conclusion： DCLHS has satisfactory clinical curative effect on reflux esophagitis of stagnated heat of liver and stomach type.