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MicroRNAs在退变椎间盘中表达与调控机制的研究进展 被引量：5

The research progress on expression and regulation mechanism of micro RNAs in degenerative intervertabral disc diseases
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摘要 椎间盘退变是一种与生活和工作方式、年龄密切相关的退行性改变,随着生活工作方式的改变及人口老龄化社会的来临,其患病率呈逐年上升趋势[1]。引起椎间盘退变的因素有年龄、生活工作条件、生物力学、遗传因素等[2-4]。病理变化表现为细胞过度凋亡引起功能细胞数量减少[5]、细胞外基质降解[6]、
作者 李小川 阮狄克
机构地区 海军总医院骨科
出处 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2015年第10期942-945,共4页 Chinese Journal of Spine and Spinal Cord
关键词 MICRORNAS 退变椎间盘 生活工作方式 细胞外基质降解 椎间盘退变 调控 细胞数量 退行性改变
分类号 R681.5 [医药卫生—骨科学] Q786 [生物学—分子生物学]
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参考文献26

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二级参考文献64

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共引文献18

同被引文献45

  • 1张益民,李汉秀,辛杰,王凤鸣.炎症因素在腰椎间盘退行性病变中的作用[J].中国临床康复,2004,8(29):6474-6475. 被引量：1
  • 2胡绪江,邵增务.外源性肿瘤坏死因子-α对腰椎间盘退变影响的实验研究[J].中国脊柱脊髓杂志,2006,16(7):541-544. 被引量：38
  • 3王宗亮,刘维钢,史建刚,尚琦松.细胞因子在椎间盘退变中作用的研究进展[J].组织工程与重建外科杂志,2007,3(1):59-60. 被引量：14
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引证文献5

二级引证文献13

中国脊柱脊髓杂志
2015年 第10期

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