医用切片石蜡的改性工艺研究

Study on technology of medical sliced paraffin modification

采用聚乙烯蜡和一种食品添加剂L为石蜡改性剂,以改性石蜡的针入度、滴熔点为指标,考察反应时间、反应温度、搅拌速度、聚乙烯蜡和添加剂L的添加量等对石蜡性能的影响。结果表明,最佳改性条件为:反应时间5 h,反应温度150℃,搅拌速度600 r/min,聚乙烯蜡添加量4%,添加剂L添加量8%。在此条件下,制备出的改性石蜡的针入度、滴熔点等符合一些地区病理科对医用切片石蜡的要求。

Using polyethylene wax and a kind of food additives named L as the modifiers of paraffin,and the modified paraffin penetration,drop melting point as index. The effects of reaction time,reaction temperature,stirring speed,the amount of polyethylene wax and L on the performance of paraffin was investigated. The result showed that the optimum modified condition were： the reaction time is 5 h,reaction temperature is 150 ℃,stirring speed is 600 r / min,polyethylene wax is 4%,L is 8%. Under this condition,the penetration,drop melting point of paraffin fit the requirements of medical sliced paraffin,it can be used to study the pathological tissue.