高血糖相关偏身投掷和舞蹈症的CT及MRI表现

Research on CT and MRI findings of Hemiballism-hemichorea induced by hyperglycemia

目的:分析高血糖相关偏身投掷和舞蹈症(HB-HC)的CT及MRI影像学表现及发病机制,提高对高血糖相关HB-HC的整体认识和诊断准确率。方法:回顾性分析5例高血糖相关HB-HC临床表现及影像学资料,通过文献分析获取其发病机制及引起特征性影像学表现的相关机制。结果:高血糖相关HB-HC临床表现单侧肢体不自主和大幅度运动。CT表现为基底节区高密度影,MRI表现为特征性壳核T1WI高信号。结论:高血糖相关HB-HC临床上比较少见,有特征性神经影像学表现,尽早诊断和治疗对患者预后良好,同时鉴别诊断显得尤为重要。故需综合考虑患者的既往病史、临床表现、实验室检查以及影像学等检查,有助于做出正确的临床诊断。

Objective：To summarize the clinicopathologia and imaging features of Hemiballism-hemichorea induced by hyperglycemia and increase the understanding of the disease and improve the accuracy of diagnosis. Methods：The imaging images and clinical manifestation of 5 cases Hemiballism-hemichorea induced by hyperglycemia were analyzed retrospectively. The disease pathogenesis and mechanism relating to the Characteristic neuroradiological findings was obtained by literature review. Results：The common clinical manifestation of Hemiballism-hemichorea induced by hyperglycemia is unilateral limb involuntary movements. CT scans typically show an area of hyperdensity in the basal ganglia and The characteristic finding on the T1-weighted MRI is high signal intensity in the contralateral putamen. Conclusion： Hemiballism-hemichorea induced by hyperglycemia is an unusual but important differential diagnosis in patients with particular neuroradiological findings as prompt diagnosis and treatment of hyperglycemia has an excellent prognosis. The correct diagnosis could be received through integrated the patient＇s past medical history, presentation, laboratory and imaging inspection into account.