程序化镇痛镇静对ICU慢性阻塞性肺疾病急性加重患者康复影响分析

Effects Analysis of Procedural Sedation Strategies for Treating Chronic Obstructive Pulmonary Disease with Acute Exacerbation in the ICU

目的探讨程序化镇痛镇静对ICU慢性阻塞性肺疾病急性加重患者康复影响。方法慢性阻塞性肺疾病急性加重患者70例按入科顺序分为治疗组与对照组各35例,两组都给予机械通气与常规护理,在此基础上治疗组加用程序化镇痛镇静策略。结果在治疗组中,使用咪达唑仑注射液和吗啡的平均剂量与总剂量都明显低于对照组(P<0.05),治疗组的机械通气时间、ICU住院日和总住院日都明显少于对照组(P<0.05),治疗组在干预期间的腹胀、口干、恶心、呕吐、感染等并发症总体发生率明显低于对照组,差异有统计学意义(P<0.05)。结论程序化镇痛镇静策略配合在ICU慢性阻塞性肺疾病急性加重患者的应用能有效提高镇痛镇静效果,促进患者的康复,同时安全性好,值得推广应用。

Objective To investigate the effects of procedural sedation strategies for treating chronic obstructive pulmonary disease with acute exacerbation in the ICU .Methods Seventy cases with chronic obstructive pulmonary disease with acute exacerbation were e -qually divided into treatment group and control group 35 cases.Patients in two groups were given mechanical ventilation with conventional care, and those in the treatment group were added with procedural sedation strategies .Results The morphine injection and midazolam injection average and total doses of the treatment group were significantly lower than the control group （P〈0.05）, the mechanical ventila-tion, ICU length of stay , and total hospital stay of the treatment group were significantly than the control group （P〈0.05）.During the intervention, the complications overall incidence rates of the bloating , dry mouth, nausea, vomiting, infections of the treatment group were significantly lower than the control group that compared to significant differences （P〈0.05）.Conclusion Procedural sedation strategies ICU for treating chronic obstructive pulmonary disease with acute exacerbation can effectively improve the analgesic sedative effect , pro-mote the rehabilitation of patients , while its security was good that should be widely applied .