是否共病焦虑障碍的女性复发性抑郁症临床特征比较

A Comparative study of clinical features for female patients with recurrent depression co-morbidity with or without anxiety disorders

目的探讨是否共病焦虑障碍的女性复发性抑郁症患者的临床特征。方法收集女性复发性单相抑郁症患者301例,根据是否共病焦虑障碍分为研究组(162例)和对照组(139例),采用人口学资料、临床特征、精神病理学、艾森克人格问卷(EPQ)神经质因子、生活应激事件量表、父母亲情关系量表(PBI)等对两组患者进行评定。结果女性复发性抑郁症患者共病焦虑障碍发生率为53.8%。两组患者在总病程、抑郁症状数、家族史、食欲减退、精神运动性激越、易激惹、焦虑、PBI控制维度/父亲、儿童期性侵犯、EPQ神经质维度评分、生活压力事件发生数、自然灾害、童年被严重忽视等方面存在显著性差异(P<0.05)。结论女性复发性抑郁症与焦虑障碍共病较为常见,共病与患者个人、家庭及社会因素有关。

Objective To explore the clinical features for female patients with recurrent depression co-morbidity with or without anxiety disorders.Methods A total of 301 female patients with recurrent depression were divided into study group（162 cases） for co-morbidity with anxiety disorders and control group （139 cases） for co-morbidity without anxiety disorders.They were assessed with demographic data, clinical data, psychopathology, neuroticism factor of Eysenck Personality Questionnaire （EPQ）, Stressful Life Events Scale and Parental Bonding Instrument Scale（PBI）.Results The prevalence rate of recurrent depression co-morbidity with anxiety disorders for female patients was 53.8%.There were significant differences on total disease course, number of depressive symptoms, family history, less appetite, psychomotor agitation, irritability, anxiety, factor score of father controlling in PBI, sexual assault in childhood, factor score of neuroticism in EPQ, number of stressful life events and natural disasters as well as being seriously neglected in childhood between two groups（P〈0.05）.Conclusion It＇s common for the female patients with recurrent depression co-morbidity with anxiety disorders, which is related to personal, family and social factors.