广州市实验大白鼠及其接触人员感染流行性出血热的调查

The survey on laboratory white rat and its contacts infected with EHF in Guang zhou

作者于1990年2～6月,对广州实验大白鼠及其接触者进行了EHF感染调查。在25个单位采集了实验大白鼠423只,EHFV抗原阳性率11.8%(50/423),抗体阳性率12.5%(58/463),总感染率12.0%(59/491)。11份EHFV抗原阳性实验大白鼠肺组织,有1份分离出EHFV。在大白鼠饲养室周围捕捉褐家鼠9只,EHFV感染率22.2%(2/9)。在21个单位采集实验大自鼠接触者血清标本89份。EHFV抗体阳性率19.1%(17/89),发病率6.7%(6/17)。其中实验室人员感染率为14.6%(7/48),发病率为8.3%(4/48);饲养员感染率为24.4%(7/48),发病率为4.8%(2/41)。从3份病人血清中1份分离到EHFV。

The investigation on the laboratory white rat and its contact infected with EHF (Epidemic Hemorragic Fever) was carried out from February to June in 1990 in Guang zhou. The speciments from 423 white rats which from 25 institutions were tested with EHFV antigen. The result showed that the positive rate was 11.8%, and positive rate with EHFV antibody was 12.5%, the total infectious rate was 12.0%. A strain of EHF virus was isolated from the lung tissure of 11 EHFV Antigen positive white rats. 9 Rattus norvegicus were caught from surrounding area of breeding laboratories from which the infectious rate of 22.2% were founded. 89 speciments from contacts —the person who get in touch with laboratory white rat from 21 institutions, its positive rate were 19.1%, and the rate of incidence was 6.7%, in which the laboratory workers such as technician and so on infected with EHF are 7 persons, the rate of whose infection was 14.6%, the rate of incidence was 8.3%, the breeder who worked at breeding side, that the rate of whose infection was 4.8%. A strain of EHF virus was isolated from three patients's serum.