饲用氧化锌替代思路研究进展

Alternative Strategy of Zinc Oxide in Feed

使用药理剂量的（2 500～4 000 mg/kg）氧化锌是防治断奶仔猪腹泻、提高其生长性能的重要手段之一,然而高锌会带来环境污染与细菌抗性等问题,目前亟需寻找有效的替代产品。本文综述了2种不同的氧化锌替代思路：以提高锌生物利用率为主的不同锌源（有机锌与碱式氯化锌）;以提高氧化锌作用效率为主的不同形式氧化锌（纳米氧化锌、氧化锌-硅酸盐复合物与多孔氧化锌）,并且提出了＂高比表面积-微米粒径＂的新型氧化锌研制思路,以实现氧化锌使用减量、环境减排的目标。

Pharmacological dosages（2500～4000 mg/kg） of ZnO have been used as effective diarrhea prophylaxis and growth promoter in weaning piglets. However, concerning consequent pollution and resistance of high-level zinc supplementation, it is imperative to find alternatives. This paper reviews two main alternatives strategies of ZnO：alternative zinc sources（e.g. organic zinc and tetrabasic zinc chloride） to improve bioavailability of zinc;alternative ZnO forms（e.g. nano ZnO, ZnO-silicate composite and porous ZnO） to improve action efficiency of ZnO. In the end,a novel strategy of alternative Zn O form, large specific surface area and micro-scale particle size, is proposed to reduce usage and pollution.