中医药治疗糖尿病肾病研究进展

Research progress of traditional Chinese medicine treatment of diabetic nephropathy

糖尿病肾病(diabetic nephropathy,DN)是引发终末期肾衰竭的主要原因,严重危害人类健康,迫切需要有效的治疗方法。近年来,我们采用循证医学的方法研究证实中医药治疗DN有一定的临床疗效,并从整体、细胞、分子等不同层次上探讨了中医药治疗DN的作用机制,发现单味中药及复方可以通过多靶点、多途径发挥治疗作用,中医药有望成为治疗糖尿病肾病的有效方法之一。本文将概述近年来本领域的研究进展,为今后的研究提供参考。

Diabetic nephropathy is the main reason of the end-stage renal failure and endanger human health seriously.Effective treatment of diabetic nephropathy is in an urgent demand.In recent years,we confirmed the good effect of TCM on diabetic nephropathy by evidence based medicine method.We also explored the treatment mechanism of TCM on diabetic nephropathy from overall level,cellular level and molecular level and found that both single herb and Chinese herbal compound can treat diabetic nephropathy by multiple targets control.TCM may become one of the effective methods for treating diabetic nephropathy.This paper will review the advances in this research field of recent years and provide references for future researches.