中西医结合治疗白塞病口腔溃疡23例临床观察

The Epiglottis Zhuyu Decoction on behalf of the Tea Treatment of Oral Cavity Ulcer Curative Effect Observation of Behcet's Disease

目的:观察会厌逐瘀汤代茶饮治疗白塞病口腔溃疡的临床疗效。方法:选取确诊为白塞病的患者46例,随机分为治疗组和对照组,对照组予沙利度胺75mg/d,治疗组在对照组基础上加会厌逐瘀汤代茶饮1500ml每日不拘时服,均连续治疗3个月。分别观察并记录治疗前、治疗后3个月期间溃疡间歇时间总和(d)和溃疡复发数目总和(个)。结果:治疗组总有效率95.45%,对照组总有效率66.67%,两组差异具有统计学意义(P<0.05)。结论:会厌逐瘀汤代茶饮联合沙利度胺治疗白塞病口腔溃疡疗效优于单纯应用沙利度胺。

Objective To observe the clinical efficacy of epiglottis Zhuyu Decoction on behalf of the tea by oral ulcer treatment of Behcet＇s disease. Methods 46 cases of Behcet＇s disease were randomly divided into treatment group and control group, treatment group was treated with thalidomide plus 75mg/d epiglottis Zhuyu Decoction on behalf of the tea 1500ml daily at any time; control group was treated with thalidomide 75mg/d. Both lasted for 3 months. 3 months before and after treatment were observed and recorded during the sum of ulcer interval time （days） and the total number of （a） the recurrence of peptic ulcer. Results The total effective rate was 95.45% in treatment group and control group in the total efficiency of 66. 67%, with significant difference between two groups （ P 〈0. 05 ）. Conclusion The epiglottis Zhuyu Decoction on behalf of the tea combined with thalidomide in treatment of oral cavity ulcer curative effect is better than the simple application of thalidomide in Behcet＇s disease.