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2型糖尿病患者瞬目反射的特点及与相关因素的关系 被引量:2

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摘要 目的探讨2型糖尿病患者瞬目反射(BR)的特点及与临床相关因素的关系。方法随机选取确诊2型糖尿病患者127例为观察组,健康志愿者28例为对照组,两组均进行BR检查,并对两组BR各波R1、R2、R'2潜伏期及R1侧间差、R2侧间差、R'2侧间差进行比较;收集观察组血糖、血脂相关指标、神经传导、F波、H反射、颈动脉彩超、下肢动脉彩超、视网膜检查等相关临床资料进行统计分析,分析其与BR的相关性。结果年龄≥60岁、病程≥5年、神经传导检查阳性患者BR阳性率升高;神经传导检查、F波、H反射阳性、合并视网膜病变的患者,R1、R2、R'2潜伏期均长于对照组。R1潜伏期与年龄、病程、LDL-C水平呈正相关。R2、R'2潜伏期与LDL-C水平呈正相关。结论神经传导、F波、H反射阳性和伴有糖尿病性视网膜病变的2型糖尿病患者,应该警惕BR环路病变的可能性,尤其对于年龄大、病程长、LDL-C水平持续显著异常的患者更加应该提高警惕,应及时了解并干预其中枢神经系统并发症的状况。
出处 《广东医学》 CAS 北大核心 2015年第20期3157-3160,共4页 Guangdong Medical Journal
基金 广州市科技惠民专项项目(编号:2014Y2-00046)
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参考文献10

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