心搏骤停后综合征患者急性肾损伤研究进展

Research Progress of Acute Kidney Injury of Patients with Post-Cardiac Arrest Syndrome

心搏骤停后综合征是心搏骤停自主循环恢复后的一种独特而复杂的病理生理过程,它包括心搏骤停后脑损伤;心搏骤停后心脏功能障碍;全身性缺血/再灌注损伤;持续性促病理因素。急性肾损伤是住院患者非常常见和严重的一种并发症。缺血/再灌注是导致心搏骤停后综合征患者出现急性肾损伤的主要原因,其治疗主要包括控制体温、早期血流动力学优化、肾脏替代治疗等。

Post-cardiac arrest syndrome is a unique and complex pathophysiologieal process after the return of spontaneous eireulatign when cardiac arrest occurs. It includes post-cardiac arrest brain injury,post- cardiac arrest myocardial dysfunction, systemic ischemia-reperfusion response and persistent precipitating pathology. Acute kidney injury is a very common and serious complication in hospitalized patients. Ischemia- repelfusion is the main cause of acute kidney injury in patients with post-cardiac arrest syndrome. The treat- ment includes： therapeutic hypothermia, early hemodynamic optimization, renal replacement therapy and 80 on.