cN0期甲状腺微小乳头状癌颈部淋巴结处理的研究进展

Research Progress of Lymph Node Dissection in Treatment of cNO Papillary Thyroid Microcarcinoma

目的分析影响甲状腺微小乳头状癌(PTMC)中央区颈部淋巴结转移的因素,以探讨对PTMC患者的治疗方式,进而改善疾病预后。方法通过检索Pub Med获取近年来的相关文献资料并对其进行综述。结果临床上PTMC患者中央区颈部淋巴结转移率仍然较高。预防性中央区颈部淋巴结清扫对于降低疾病局部复发率及明确疾病分期以指导术后治疗至关重要。结论对于术前已证实出现颈部淋巴结转移的PTMC,应进行中央区颈部淋巴结清扫。对于c N0期患者,应对高危或存在高风险的PTMC患者进行预防性中央区颈部淋巴结清扫。

Objective To analyze the predictive factors for central lymph node metastasis in papillary thyroid microcarcinoma（PTMC）,and explore the treatment method for the patients with PTMC.Method The literatures were reviewed according to the results searched from PubMed in recent years.Results Central lymph node metastases were common in the patients with PTMC.It was important for prophylactic central lymph node dissection so it might reduce the local recurrence and comfirm the clinical staging,further more provide the strategies for the postoperative therapy.Conclusions Lymphadenectomy is necessary for patients with lymph node metastasis.Prophylactic central lymph node dissection should be performed for patients without lymph node metastasis but with one risk factor or more.