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宝石能谱CT对宫颈癌区域淋巴结定性诊断中的价值 被引量:6

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摘要 目的:探讨宝石能谱CT在宫颈癌区域淋巴结定性诊断中的价值。方法:2014年1-6月经病理学证实且行宝石能谱CT分期检查发现区域淋巴结肿大宫颈鳞状细胞癌34例,通过对比患者已知宫颈原发灶与区域肿大淋巴结进行能谱分析推测诊断出增大淋巴结是否为转移性癌。所有患者同时予18F-FDG PET-CT检查或穿刺活检,以PET-CT检查结果或穿刺活检病理学结果为诊断标准,以Yerushalmy 模式计算宝石能谱CT在宫颈癌区域淋巴结定性诊断的敏感度、特异度、阳性预测值、阴性预测值、约登指数来评价判断淋巴结是否转移结果。绘制ROC曲线,计算曲线下面积比较不同方法的诊断准确性。结果:34例宫颈癌患者宝石能谱CT淋巴结诊断结果与标准诊断(即PET-CT诊断结果和病理学诊断结果)对照进行分析得出特异度为46.77%,灵敏度为92.17%,约登指数为0.39;分别对两种诊断结果做一致性检验和配对卡方检验,诊断结果基本一致(Kappa =0.428),诊断水平有差异(P <0.001)。 ROC曲线下面积为0.695(P <0.001,CI:0.607-0.782)。结论:宝石能谱 CT对于宫颈癌分期诊断有较好的指导作用,但尚不能作为区域淋巴结定性诊断的依据。
作者 张宽
出处 《实用医学杂志》 CAS 北大核心 2015年第20期3373-3375,共3页 The Journal of Practical Medicine
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参考文献9

  • 1Kawaguchi R, Furukawa N, Kobayashi H, et al. Posttreatment cut-off levels of squamous cell carcinoma antigen as a prognostic factor in patients with locally advanced cervical cancer treated with radiotherapy [J]. J Gynecol Oncol, 2013,24 (4) :313-320.
  • 2张杰平,唐明灯,林端瑜,蔡志华.^(18)F-FDG PET/CT在诊断宫颈癌原发灶和盆腔淋巴结转移中的价值[J].福建医科大学学报,2013,47(6):382-385. 被引量:5
  • 3林晓珠,李卫侠,朱延波,董海鹏,吕培杰,缪飞,李剑颖,沈云,陈克敏.宝石能谱CT在肿瘤诊断中的初步应用[J].诊断学理论与实践,2010,9(2):155-160. 被引量:127
  • 4Engin G, Kueucuk S, Olemz H, et al. Corralation of clinical and MRI staging in cervical carcinoma treated with radiation therapy : A single-center eaperience [J ]. Diagn Interv Radiol, 2011, 17(1) :44-51.
  • 5漆辉雄,杜珂,孙秋实,李泉.调强放疗同步化疗联合热疗治疗中晚期宫颈癌的临床观察[J].实用医学杂志,2013,29(17):2928-2929. 被引量:37
  • 6黄裕,姜青明,王冬,周琦.特殊病理类型宫颈癌24例临床病理分析[J].肿瘤防治研究,2012,39(7):885-886. 被引量:2
  • 7Matsumoto K, Jinzaki M, Tanami Y, et al. Virtual monochromatic spectral imaging with fast kilovoltage switching: improved image quality as compared with that obtained with conventional 120- kVp CT [ J ]. Radiology, 2011,259 ( 1 ) : 257-262.
  • 8Deng K, Liu C, Ma R, et al. Clinical evaluation of dual-energy bone removal in CT angiography of the head and neck: comparison with conventional bone-subtraction CT angiography [J]. Clin Radiol, 2009,64(5):534-541.
  • 9Kalender WA. CT: the unexpected evolution of an imaging modality [J]. Eur Radiol, 2005,15(S4) :D21-D24.

二级参考文献34

  • 1Sorrano MF,Katz M,Yah Y,et al.Percentage of highgrade carcinoma as a prognostic indicator in patients with renal cell carcinoma[J].Cancer,2008,113(3):477-483.
  • 2Liu Y,Song Q,Jin HT,et al.The value of multidetectorrow CT in the preoperative detection of pancreatic insulinomas[J].Radiol Med,2009,114(8):1232-1238.
  • 3Ichikawa T,Peterson MS,Federle MP,et al.Islet cell tumor of the pancreas:biphasic CT versus MR imaging in tumor detection[J].Radiology,2000,216(1):163-171.
  • 4Thoeni RF,Mueller-Lisse UG,Chan R,et al.Detection of small,functional islet cell tumors in the pancreas:selection of MR imaging sequences for optimal sensitivity[J].Radiology,2000,214(2):483-490.
  • 5Del Gaudio A,Solidoro G,Del Gaudio GA,et al.Hepatic growths mimicking adrenal tumors[J].Hepatogastroenterology,1998,45(23):1742-1747.
  • 6Fuhrman SA,Lasky LC,Limas C.Prognostic significance of morphologic parameters in renal cell carcinoma[J].Am J Surg Pathol,1982,6(7):655-663.
  • 7Minervini A,Lilas L,Minervini R,et al.Prognostic value of nuclear grading in patients with intracapsular (pT1-pT2) renal cell carcinoma.Long-term analysis in 213 patients[J].Cancer,2002,94(10):2590-2595.
  • 8Hodgson DC,. Grunfeld E, Gunraj N, et al. A population-based study of follow-up care for Hodgkin lympho- ma survivors: opportunities to im- prove surveillance for relapse and late effects[J]. Cancer, 2010, 116(14): 3417-25.
  • 9Singh P, Nicklin J, Hassall T. Neo- adjuvant chemotherapy followed by radical vaginal tracheleetomy and ad- juvant chemotherapy for clear cell cancer of the cervix: a feasible ap proach and review[J]. Int J Gynecol Cancer,20l1,21(1) :137-40.
  • 10EI-Sahwi K, Bellone S, Cocco E, et al. In vitro activity of pertuzumab in combination with trastuzumab in u- terine serous papillary adenocarcino ma[J]. Br J Cancer,2010, 102(1):134-43.

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