我院2011-2014年结直肠癌患者化疗用药分析

Analysis of the Application of Antineoplastic Drugs in Patients with Colorectal Cancer in Our Hospital during 2011-2014

目的:为结直肠癌患者化疗提供方案以及用药参考。方法:查阅我院2011-2014年化疗的结直肠癌住院患者的病历及医嘱,对化疗方案和药物的使用及用药不合理现象进行回顾性统计、分析。结果:共纳入结直肠癌患者593例,化疗频次1 940次,主要从化疗的适应证、方案的选择、化疗过程、化疗的时间及周期等方面对化疗方案选择进行分析;用药不合理409例,主要从药物剂量、溶剂选择、药物浓度等方面进行统计分析,不合格率为21.08%。结论:我院结直肠癌患者抗肿瘤药的使用以及化疗方案的选择基本合理,但仍存在一定的不足,在今后的临床应用中,有待进一步改进。

OBJECTIVE： To provide reference for medication and chemotherapy in patients with colorectal cancer. METH- ODS ： Through retrospective study, case histories and doctor＇ s advice of the colorectal cancer patients receiving chemotherapy in our hospital during 2011-2014 were consulted to analyze the chemotherapy, medication and irrational drug use. RESULTS： A total of 593 cases of colorectal cancer patients with chemotherapy frequency of 1 940 times were collected to analyze the choice of che- motherapy regimen mainly from the following aspects： indications of chemotherapy, choice of chemotherapy regimen, chemothera- py process and chemotherapy period. There was 409 cases of irrational drug use according to the analysis of drug dosage, selection of solvents and drug concentration, the unqualified rate was 21.08% . CONCLUSIONS： The medication and chemotherapy in pa- tients with colorectal cancer in our hospital are basically rational, but there are still certain problems and shortcomings. In future clinical applications, the medication and chemotherapy need to be improved.