自体静脉神经导管修复周围神经缺损的研究进展

RESEARCH PROGRESS OF AUTOLOGOUS VEIN NERVE CONDUIT FOR REPAIR OF PERIPHERAL NERVE DEFECT

目的综述自体静脉神经导管修复周围神经缺损的研究进展。方法查阅近年国内外有关自体静脉神经导管修复周围神经缺损的研究文献,并进行总结分析。结果大量基础研究和临床应用表明,自体静脉神经导管能够修复短距离神经缺损,尤其是导管复合有各种自体非神经组织、细胞、生长因子等情况时,其效果接近自体神经移植。结论自体静脉神经导管修复神经缺损可以较好地作为自体神经移植的补充,改进自体静脉神经导管以修复周围神经缺损是今后研究方向。

Objective To summarize the research progress of autologous vein nerve conduit for the repair of peripheral nerve defect. Methods The recent domestic and foreign literature concerning autologous vein nerve conduit for repair of peripheral nerve defect was analyzed and summarized. Results A large number of basic researches and clinical applications show that the effect of autologous venous nerve conduit is close to that of autologous nerve transplantation in repairing short nerve defect, especially the compound nerve conduit has a variety of autologous nerve tissue, cells, and growth factors, etc. Conclusion Autologous vein nerve conduit for repair of non-nerve defect can be a good supplement of autologous nerve graft, improvement of autologous venous catheter to repair peripheral nerve defect is the research direction in the future.