经皮测黄胆仪检测值分组在1200例高胆红素血症诊治中的临床应用

Clinical applications of 1 200 cases of transcutaneous jaundice detection values grouping in the diagnosis and treatment of hyperbilirubinemia

目的评价对经皮黄疸仪检测值分组对诊治高胆红素血症的临床价值。方法对1 200例高胆红素血症足月新生儿及婴儿,依据经皮黄疸胆仪检测值的高低进行分组,经皮胆红素测定值任意部位〉13mg/dl为A组125例,〉10~12.9mg/dl为B组468例,7~9.9mg/dl为C组421例,5~6.9mg/dl为D组186例,根据分组分别采取不同的治疗和干预措施,A组采用光疗及综合治疗,B组采用口服茵栀黄和枯草杆菌二联活菌颗粒（妈咪爱）治疗,C组口服妈咪爱治疗,D组未给予药物治疗仅进行日光浴和口服葡萄糖水处理。结果 4组经治疗〉12d后内经皮胆红素测定值降至〈5mg/dl患者比例均〉90%。结论经皮胆红素测定（经皮黄疸仪）值分组对诊治新生儿高胆红素血症有较高的临床实用价值。

Objective To evaluate the clinical value of percutaneous jaundice detection value grouping in the diagnosis and treatment of hyperbilirubinemia. Methods 1 200 cases of full-term neonates and infants with hyperbilirubinemia were grouped according to the level of percutaneous biliary jaundice detection values. The transcutaneous bilirubin measurements at any site 〉13 mg / dl was as group A（ n = 125 cases）, 〉10 ~ 12. 9mg / dl as group B（ n = 468 cases）,7 ~ 9. 9mg / dl as the group C（ n = 421 cases）,5 ~ 6. 9mg / dl as the D group（ n = 186 cases）. The treatment and intervention measures were taken according to different grouping. The group A received light therapy and combined therapy; the group B was treated with oral Yinzhihuang and Combined Bacillus Subtilis and Enterococcus Faecium Granules with Multivitamines,Live（ MAMIAI） therapy; the group C was given MAMIAI for treatment; the group D was not given drug treatment,but only for receiving sunbathing and oral glucose water treatment. Results After treatment for 12 days,the proportions of patients whose transcutaneous bilirubin measurement value dropped to below 5mg / dl were all more than 90% in the 4 groups. Conclusion Percutaneous bilirubin（ transcutaneous jaundice meter） detection values grouping has high clinical value in the diagnosis of neonatal hyperbilirubinemia.