布地奈德吸入对儿童咳嗽变异性哮喘的疗效分析

目的：探讨布地奈德吸入对儿童咳嗽变异性哮喘的疗效。方法：回顾性研究2013年1月-2014年1月本院儿科收治的变异性哮喘儿童患者82例,随机分为实验组和对照组,每组41例,对照组给予口服咳必清等常规镇咳药物治疗,实验组在对照组用药基础上加用布地奈德气雾吸入剂治疗,治疗周期为4周,观察记录两组临床治疗情况,如治疗后缓解时间和咳嗽消失时间。结果：经过4周治疗,实验组咳嗽缓解时间及咳嗽消失时间均短于对照组,差异具有统计学意义（P〈0.05）;治疗后,实验组、对照组的总有效率分别为94.34%和76.92%,实验组总有效率明显高于对照组,差异具有统计学意义（P〈0.05）。结论：加用布地奈德吸入治疗儿童变异性哮喘效果明显,安全,值得临床推广。

Objective ：To investigatethe efficacy ofinhaledbudesonidein childrencough variantasthma.Methods ：A retrospective studyin January 2013 -January 2014pediatric patientsatthe pediatrichospitaltreated82 cases ofvariant asthmawere randomlydivided into treatmentand control groups, each group41 cases, patients treated withoralbecarbetapentaneantitussiveagentsand otherconventional dosetherapy, the controlgronp was basedon the use ofbudesonideinhalationtherapy, the treatment period offour weeks, observe and compare theclinical efficaeyin patients withremissiontimeaftertime, and cough disappear.Results After4 weeks of treatment, patients treatedcoughand coughdisappearedremission timeperiodwercless than the controlgroup, two groups, the difference was statisticallysignificanceat（P〈0.05 ）;aftertreatment, the total efficiency ofthe treatmentand control groups, respectively 94.34% and 76.92%, the total efficiency ofthe treatmentgroupwas significantly higherin both groups,the difference was statisticallysignificanceat （P〈0.05）. Conclusion Budesonideinhalation treatmcntof childrenvariant asthmais effective,safe, worthy of promotion.