摘要
目的优选止咳平喘颗粒处方药材的提取工艺。方法以麻黄碱、连翘酯苷A提取率为指标,以乙醇体积分数、乙醇倍量、提取时间、提取次数为因素,采用L9(34)正交试验对提取工艺进行优选。结果最佳提取工艺条件为65%乙醇,回流提取2次,每次8倍量,每次1 h。结论优选的止咳平喘颗粒处方药材提取工艺条件合理、可行。
Objective To optimize extraction process on Zhike Pingchuang Granula prescription by orthogonal test. Methods With extracting rates of ephedrine and forsythoside A as indexes, meanwhile ethanol concentration, amount of solvent, extraction duration, and extraction times as investigation factors, conditions for extraction process were optimized by L9（34） orthogonal test. Results The optimum extraction process conditions were as follows： eight volumes of 60% ethanol and reflux extracting for two times with 1 h for each time. Conclusion The optimized extraction technology is reasonable and feasible for Zhike Pingchuang Granula prescription.
出处
《现代药物与临床》
CAS
2015年第10期1208-1211,共4页
Drugs & Clinic
关键词
止咳平喘颗粒
麻黄碱
连翘酯苷A
提取工艺
正交试验
Zhike Pingchuang Granula
ephedrine
forsythoside A
extraction process
orthogonal test
