中药注射剂溶媒选择统计分析

Statistical analysis of solvent selection in traditional Chinese medicine injections

目的:结合六安市中医院中药注射剂溶媒使用情况,讨论不同溶媒对中药注射剂的稳定性和不溶性微粒的影响,为临床使用中药注射剂合理选择溶媒提供理论依据和参考。方法:统计调查限定中药注射剂溶媒的品种,用等距离随机抽样法调取六安市中医院药静配中心2015年第1季度的中药注射剂处方,对其溶媒使用情况进行统计分析。结果:共调取483张处方,溶媒选择与说明书不一致的有59张,占12.2%。具体品种有茵栀黄注射液,参麦注射液,舒血宁注射液,丹红注射液,生脉注射液,鸦胆子油乳,复方苦参注射液。结论:临床在应用中药注射剂时,应当严格遵从药品说明书,选择合适的溶媒,同时还应关注有关中药注射剂配伍方面的最新研究成果和动态。

Objective： According to the Institute of traditional Chinese medicine injection solvent usage, discusses the influence of different solvents on the stability of traditional Chinese medicine injections and insoluble particles, to provide a theoretical basis and reference for reasonable selection of clinical use of traditional Chinese medicine injection solvent. Method： Statistical investigation limited varieties of traditional Chinese medicine injection solvent, the distance between random sampling method was used to obtain our hospital static distribution center in 2015 in the first quarter of prescriptions of traditional Chinese medicine injection, the solvent usage for statistical analysis. Results： A total transfer of 483 prescriptions, selection of solvent and specifications are inconsistent with 59, accounting for 12.2%. Specific varieties of Yinzhihuang injection, Shenmai injection, Shuxuening injection, Danhong injection, Shengmai injection, Brucea javanica oil emulsion, compound matrine injection. Conclusion ： Clinical application of traditional Chinese medicine injection in shall strictly comply with the drug instructions, select the appropriate solvent, attention should also be paid to Chinese medicine injections combined with the latest research results and dynamic.