严重感染和感染性休克液体复苏晶胶体选择——对大型试验研究结果的思考

Selection of crystalloid or colloid in fluid resuscitation of patients with severe sepsis or septic shock: thoughts about the results from large-scale experiments

严重感染和感染性休克是重症医学(critical care medicine,CCM)常见的临床综合征,其早期目标导向治疗(early goal-directed therapy,EGDT)中以液体复苏为首要救治措施,而在液体复苏过程中晶体溶液与胶体溶液的选择问题一直存在争议。文章就近年来严重感染和感染性休克行液体复苏时,晶体溶液(生理盐水和平衡盐溶液)和胶体溶液(天然胶体和人工胶体)选择的共识理论基础和热点争议问题进行阐述。

Severe sepsis and septic shock are common clinical syndromes in critical care medicine（CCM）, and fluid resuscitation is the primary treatment in the early goal-directed therapy（EGDT）. However, the selection of crystalloid or colloid in fluid resuscitation has been controversial. In this article, we will discuss the theoretical basis of consensus and hotspot issues in recent years about the selection of crystalloid or colloid in fluid resuscitation of patients with severe sepsis or septic shock.