肿瘤坏死因子α和白细胞介素1β对新生儿缺血缺氧性脑病的临床诊断价值

The Clinical Diagnosis Value of Tumor Necrosis Factor Alpha and Interleukin 1 Beta for Neonatal With Hypoxic Ischemia Encephalopathy

目的探讨肿瘤坏死因子α和白细胞介素1β对新生儿缺血缺氧性脑病的诊断意义。方法收集2012年2月-2015年2月我院诊断缺血缺氧性脑病的40例新生儿作为为研究组。对照组为同期我院健康分娩的新生儿40例。对比两组出生24 h肿瘤坏死因子α和白细胞介素1β;研究组出生24 h与治疗后出院时肿瘤坏死因子α和白细胞介素1β水平。结果两组出生24 h肿瘤坏死因子α和白细胞介素1β结果比较,P〈0.05,差异具有统计学意义,且研究组出生24 h与治疗后出院时肿瘤坏死因子α和白细胞介素1β结果比较,P〈0.05,差异具有统计学意义。结论肿瘤坏死因子α和白细胞介素1β可较好的判断新生儿缺血缺氧性脑病疾病严重程度,对判断预后有较好的指导意义。

Objective To study the tumor necrosis factor alpha and interleukin 1 beta significance to the diagnosis of neonatal hypoxic ischemia encephalopathy.Methods Selected 40 cases wiht ischemia anoxic encephalopathy from February 2012 to February 2015 in our hospital as the study group. The 40 cases control for the same period in our delivery of neonatal health as the control group. Compared two groups as born 24 hours of tumor necrosis factor alpha and interleukin 1 beta, ande the team was born 24 hours and discharged after treatment level of tumor necrosis factor alpha and interleukin 1 beta.Results Compared two groups were born 24 hours of tumor necrosis factor alpha and interleukin 1 beta results,P〈0.05, had difference statistically significance, the study group was born 24 hours and discharged after treatment of tumor necrosis factor alpha and interleukin 1 beta result,P〈0.05, had difference statistically significance. ConclusionTumor necrosis factor alpha and interleukin 1 beta can better determine neonatal hypoxic ischemia encephalopathy disease severity, and is a better guide to prognosis.