厄贝沙坦联合酒石酸美托洛尔片治疗老年心房颤动患者的临床疗效

Clinical Efficacy of Irbesartan Combined with Metoprolol in Treatment of Elderly Patients with Atrial Fibrillation

目的探讨厄贝沙坦联合酒石酸美托洛尔片治疗老年心房颤动患者的临床疗效。方法选取2014年1—12月在河南省平舆县人民医院就诊的老年心房颤动患者资料84例,按随机数字表法将其分为试验组和对照组,各42例。对照组患者口服酒石酸美托洛尔片,试验组患者在对照组基础上口服厄贝沙坦,比较两组患者的临床疗效、心房颤动发作次数及持续时间。结果试验组患者总有效率为90.5%,明显高于对照组的73.8%,差异有统计学意义(P<0.05);试验组患者心房颤动发作次数明显少于对照组,持续时间明显短于对照组,差异均有统计学意义(均P<0.05)。结论厄贝沙坦联合酒石酸美托洛尔片治疗老年心房颤动临床疗效明显,可避免或减少心房颤动发作。

Objective To evaluate the clinical efficacy of irbesartan combined with metoprolol in treatment of elderly patients with atrial fibrillation.Methods From January 2014 to December 2014,84 patients with atrial fibrillation were randomly divided into study group and control group by random digits table method,42 cases in each group.Control group was treated with oral times his Le Ke,the patients in the treatment group in the control group on the basis of oral administration of irbesartan,compared two groups of patients with clinical curative effect,atrial fibrillation attack frequency and duration.Results Patients in the study group,the total efficiency was 90.5%,significantly higher than that of 73.8% in the control group,the difference was statistically significant（P〈0.05）;study group of patients with atrial fibrillation episodes was significantly less than that of the control group,duration was significantly shorter than that of the control group,the differences were statistically significant（P〈0.05）.Conclusion Irbesartan combined with metoprolol in treatment of elderly patients with atrial fibrillation clinical curative effect,can avoid or reduce the onset of atrial fibrillation.