小金丸联合青霉素治疗小儿急性肠系膜淋巴结炎临床疗效

Clinical effect of Xiaojin pill combined with penicillin in the treatment of pediatric mesenteric lymphadenitis

目的探讨小金丸联合青霉素治疗小儿急性肠系膜淋巴结炎的临床疗效。方法急性肠系膜淋巴结炎患儿68例,随机分为实验组和对照组,各34例。对照组患儿单纯给予青霉素钠,实验组患儿在此基础上加用小金丸口服,10 d后比较两组临床疗效及主要症状消失时间。结果实验组总有效率(91.2%)高于对照组(76.5%),差异有统计学意义(P<0.05);实验组主要症状(腹痛、发热、恶心/呕吐)、肠系膜肿大淋巴结消失时间较对照组短(P<0.05)。结论对于小儿急性肠系膜淋巴结炎,采用小金丸口服联合输注青霉素疗效确切,值得临床应用。

Objective To investigate clinical effect of Xiaojin pill combined with penicillin in the treatment of pediatric mesenteric lymphadenitis. Methods A total of 68 children with mesenteric lymphadenitis were randomly divided into experimental group and control group, with 34 cases in each group. The control group received single penicillin sodium, and the experimental group received additional Xiaojin pill by oral administration. Comparisons were made after 10 d on clinical effects and main symptoms disappearance time between the two groups. Results The experimental group had higher total effective rate （91.2%） than the control group （76.5%）, and their difference had statistical significance （P〈0.05）. The experimental group also had shorter disappearance time of main symptoms （stomachache, fever, nausea/emesis） and mesenteric swelling lymph nodes than the control group （P〈0.05）. Conclusion Implement of Xiaojin pill by oral administration combined with penicillin shows precise effect for pediatric mesenteric lymphadenitis, and this method is worthy of clinical application.