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基层医院心房颤动、心房颤动合并脑卒中患者华法林抗凝的应用现状 被引量:1

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摘要 目的了解心房颤动、心房颤动合并脑卒中患者华法林抗凝冶疗的状况,提高对心房颤动、心房颤动合并脑卒中患者抗凝治疗必要性的认识。方法心内科、神经内科的住院患者800例,对全部患者的临床资料进行回顾性分析及电话访问。结果神经内科得到抗凝治疗的仅占心房颤动合并脑卒中患者的32.2%。大多数患者仅给予抗血小板治疗。心内科心房颤动患者中,口服华法林抗凝治疗者有2例发生脑卒中,发生率为3.13%;口服阿司匹林抗血小板聚集治疗患者有5例发生脑卒中,发生率8.06%。结论华法林抗凝知晓率使用率低,治疗率、监测率、达标率均偏低。基层医院仍需加强医生对华法林规范抗凝治疗的认识,努力缩小临床实践与循证医学证据和指南推荐之间的差距。
出处 《中国实用医药》 2015年第28期157-158,共2页 China Practical Medicine
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  • 1Minamino T, Kitakaze M, Sanada S,et al. Increased expression of P-selectin on platelets is a risk factor for silent cerebral infarction in patients with atrial fibrillation. Circulation, 1998, 98: 1721-1727.
  • 2Kamath S,Blann A D, Caine G J. Platelet P-selectin levels in relation to plasma soluble P-selectin and β-thromboglobulin levels in atrial fibrillation. Stroke, 2002,33:1237-1242.
  • 3Li-Saw-Hee F L, Blann A D, Gurney D, et al. Plasma von willebrand factor, fibrinogen and soluble P-selectin levels in paroxysmal, persistent and permanent atrial fibrillation :effects of cardioversion and return of left atrial fibrillation. Eur Heart J ,2001, 22: 1741-1747.
  • 4Li-Saw-Hee F L,Blann A D,Lip G Y H. A cross-sectional and diurnal study of thrombogenesis among patients with chronic atrial fibrillation. J Am Coll Cardiol, 2000,35: 1926-1931.
  • 5Conway D S, Heeringa J, Van Der Kuip D A, et al. Atrial fibrillation and the prothrombotic state in the elderly. The Rotterdam Study . Stroke, 2003,34: 413-417.
  • 6Naab M, Al-Saady A J, Have N, et al. von Willebrand factor and tissue factors expressions increased in the atrial tissue of the fibrillating atrium . J Am Coll Cardiol, 2001, 37 (Suppl A): 113A-113A.
  • 7Lip GYH, Blann A. von Willebrand factor: a marker of endothelial dysfunction in vascular disorders? Cardiovasc Res, 1997,34 :255-265.
  • 8Heppell R M, Berkin K E, Mclenachan J M, et al. Haemostatic and haemodynamic abnormalities associated with left atrial thrombosis in nonrhumatic atrial fibrillation. Heart, 1997, 77: 407-411.
  • 9张新江,周大柱.血小板形态变化与脑梗死[J].国外医学(脑血管疾病分册),1997,5(4):197-199. 被引量:56
  • 10张菲斐,张静,沈玉祥.经食道超声心动图和凝血指标评估房颤栓塞危险性的价值[J].心血管病学进展,1999,20(3):164-167. 被引量:6

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