摘要
肺纤维化是肺组织受损后的病理性修复过程，其主要特征是肺泡结构的破坏，肌成纤维细胞增殖和细胞外基质的沉积，而赖氨酸氧化酶对细胞外基质的沉积起重要作用，本文就赖氨酰氧化酶目前在肺纤维化中研究作一简要综述。
Pulmonary fibrosis is pathological repair process after lung injury,which is characterized by the loss of alveolar structures and functions following apoptosis of epithelial and endothelial cells, proliferation of fibroblasts and excessive deposition of extracellular matrix. And lysyl oxidase plays an important role on the deposition of extracellular matrix. The paper briefly reviews current research of lysyl oxidase in pulmonary fibrosis.
出处
《国际呼吸杂志》
2015年第21期1659-1662,共4页
International Journal of Respiration
基金
国家自然科学基金资助项目（81272071、81471891）
