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miRNAs在子宫内膜癌中作用机制的研究进展 被引量:1

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摘要 微小RNAs是与肿瘤发展相关的短链非编码RNAs,并且在肿瘤的发生和转移中发挥着重要作用,这些微小RNA通过降解信使RNA或抑制翻译来靶向调控基因表达。每一种微小RNAs可以调节数百个靶基因。在肿瘤的发展过程中,微小RNAs的异常表达可以使肿瘤抑制基因失去活性或活化癌基因,另外可以促进肿瘤形成。在这篇文章中,我们将几种微小RNAs在子宫内膜癌中致病机制予以综述。
出处 《中国优生与遗传杂志》 2015年第11期4-6,共3页 Chinese Journal of Birth Health & Heredity
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