胎儿不同类型胼胝体发育不全的MRI与超声诊断对比分析

Comparative study of ultrasonography and MRI in diagnosis of different types of agenesis of the corpus callosum in fetus

目的探讨MRI与超声在胎儿不同类型胼胝体发育不全(ACC)的产前诊断价值。方法对25例经超声及MRI同时检查后诊断为或疑诊为胎儿胼胝体发育不全的影像资料与随访结果进行对比分析,分别分析比较完全型胼胝体发育不全(CACC)、部分型胼胝体发育不全(PACC)及复杂型ACC合并的颅内异常MRI与超声诊断结果。结果 25例胎儿产前超声诊断CACC 14例,可疑诊断CACC 2例,诊断PACC 1例,可疑诊断PACC 6例,共漏误诊ACC 5例,发现诊断合并颅内其它异常6例。25例胎儿产前MRI诊断CACC 15例,诊断PACC 6例,可疑诊断PACC 2例,排除超声可疑诊断为PACC者2例,发现诊断合并颅内其它异常10例。结论超声与MRI两种方法产前诊断CACC的灵敏度无差异;在诊断PACC及ACC合并的颅内其它异常方面,MRI灵敏度优于超声。

Objective：To explore the value of magnetic resonance imaging（MRI）and ultrasonography in prenatal diagnosis of agenesis of the corpus callosum（ACC）in fetuses. Methods：The imaging findings in 25 fetuses with ACC diagnosed or suspected by ultrasonography and MRI were compared with the follow-up results including postnatal MR imaging and autopsy findings. ACC was divided to complete agenesis of the corpus callosum（CACC）,partial agenesis of the corpus callosum（PACC）and complicated agenesis of the corpus callosum with intracalvarium abnormality. Results：Of 25 cases by prenatal US diagnosis,CACC was diagnosed in 14 cases and suspected in 2 cases;PACC was diagnosed in 1 case and suspected in 6case;5 cases of ACC weren′t diagnosed;6 cases complicated ACC with other intracalvarium abnormality were found. Of 25 cases by prenatal MRI diagnosis of 25 cases,CACC were diagnosed in 15 cases;PACC were diagnosed in 6 cases and suspected in 2 cases;2 cases with PACC diagnosed by ultrasonography were excluded by MRI,10 cases complicated ACC with other intracalvarium abnormality were diagnosed. Conclusion：MRI is highly consistent with ultrasonography in the prenatal diagnosis of CACC. However,in the prenatal diagnosis of PACC and ACC with other intracalvarium abnormality,MRI is obviously superior to ultrasonography.